Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Azido-PEG5-acid | 1425973-16-5 | >98.0% | 335.35 | C13H25N3O7 | 10 G
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Azido-PEG5-acid is an azide-terminated five-unit polyethylene glycol (PEG5) acid linker used for bioconjugation and linker synthesis. It functions as a click-chemistry reagent capable of undergoing azide-alkyne cycloaddition reactions and is commonly used in PROTAC and antibody-drug conjugate assembly.
- Azide functional group enables copper-catalyzed and strain-promoted click reactions.
- Five-unit PEG spacer provides solubility and flexibility for conjugation.
- High purity supports synthetic and bioconjugation applications.
- Available in multiple pack sizes for scalable workflows.
- Stable under recommended storage conditions to preserve reactivity.
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Medchemexpress LLC (S,R,S)-AHPC-C6-PEG3-C4-Cl | 1835705-55-9 | MFCD31560478 | 97.0% | 751.42 | C38H59ClN4O7S | 1 G
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(S,R,S)-AHPC-C6-PEG3-C4-Cl is a VHL ligand-linker conjugate designed as a building block for PROTAC synthesis and ligand-linker conjugate development in targeted protein degradation research. It contains an (S,R,S)-configured AHPC VHL ligand connected via a six-carbon PEG3 linker with a terminal chloro group to enable downstream conjugation.
- Useful as a VHL (E3 ligase) ligand building block for degrader design.
- C6-PEG3 linker provides flexibility and spacer length for bifunctional molecules.
- Terminal chloro group enables nucleophilic substitution or further functionalization.
- Characterized by analytical data including HPLC and LC-MS for batch confirmation.
- Provided as a solid suitable for synthetic chemistry workflows and storage under controlled conditions.
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Medchemexpress LLC Boc-NH-PEG3-propargyl | 1333880-60-6 | 97.0% | C14H25NO5 | 100 MG
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Boc-NH-PEG3-propargyl is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules
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Medchemexpress LLC m-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 100 MG
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m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- One ligand for an E3 ubiquitin ligase
- The other ligand for the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Azido-PEG5-acid | 1425973-16-5 | MFCD23726612 | ≥98.0% | 335.35 | C13H25N3O7 | 1 G
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Azido-PEG5-acid is a PEG-based, azide-terminated 5-unit linker used for bioconjugation and click chemistry. It is water soluble and commonly used as a linker in PROTAC and ADC synthesis, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC).
- Azide functional group for CuAAC and SPAAC
- Five-unit PEG spacer provides water solubility
- Molecular weight 335.35 g/mol
- CAS number 1425973-16-5
- Purity ≥98.0%
- Appearance: colorless to light yellow liquid
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month)
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Medchemexpress LLC N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) | 2112737-19-4 | > 96% | C38H76N2O16 | 100 MG
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N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, with one ligand targeting an E3 ubiquitin ligase and the other targeting a specific protein. These molecules function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and not sold to patients.
- Peg-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Bis-PEG5-NHS ester | 756526-03-1 | MFCD11041118 | 99.8% | 532.50 g·mol⁻¹ | C22H32N2O13 | 100 MG
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Bis-PEG5-NHS ester is a bifunctional polyethylene glycol (PEG) linker bearing two N-hydroxysuccinimide (NHS) ester groups. It is designed for amine-targeted bioconjugation and is commonly used in the synthesis of antibody-drug conjugates (ADCs) and proteolysis targeting chimeras (PROTACs).
- Bis-functional PEG5 spacer with two NHS ester reactive groups.
- Suitable for amine coupling and bioconjugation workflows.
- High purity, analytical grade material for research use only.
- Molecular weight approximately 532.50 g·mol⁻¹.
- Soluble in DMSO at about 100 mg/mL; ultrasonic assistance recommended.
- Provided in small-scale quantities for laboratory synthesis and linker optimization.
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Medchemexpress LLC Tos-PEG3-CH2COOtBu | 1530778-24-5 | 418.50 | 5 G
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Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules designed with two different ligands connected by a linker, one for an E3 ubiquitin ligase and another for the target protein, exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![Medchemexpress LLC Hydroxylamine, o-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 | C8H18N4O4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202345.png-250.jpg)
Medchemexpress LLC Hydroxylamine, o-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 | C8H18N4O4 | 25 MG
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Aminooxy-PEG3-azide is a bifunctional PEG-based linker bearing an aminooxy group and an azide group, suitable for conjugation chemistry. It serves as a non-cleavable three-unit PEG spacer for synthesis of antibody-drug conjugates and PROTACs, and enables click chemistry reactions such as CuAAC and SPAAC.
- Used as a non-cleavable three-unit PEG linker for conjugation chemistry
- Contains aminooxy and azide functional groups for orthogonal conjugation
- Compatible with CuAAC and SPAAC click reactions
- Molecular weight 234.25 and formula C8H18N4O4
- Typical purity 95.0% (NMR)
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Medchemexpress LLC 2,4-D isooctyl ester | 25168-26-7 | 97.2% | 10 MM 1 ML
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2,4-D isooctyl ester is a selective herbicide of the chlorophenoxy compound family, known for its higher boiling point, low volatility, and minimal drift. It is effective in managing broadleaf weeds across various environments, including crops, lawns, and forests.
- Selective herbicide
- Chlorophenoxy compound
- Higher boiling point
- Low volatility
- Minimal drift
- Utilized to manage broadleaf weeds
- Suitable for use in crops, lawns, and forests
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Medchemexpress LLC Tr-PEG3-OH | 133699-09-9 | MFCD22574815 | 99.6% | 392.49 g/mol | C25H28O4 | 1 G
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Tr-PEG3-OH is a non-cleavable three-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) and PROTACs. It acts as a short, hydrophilic spacer to improve payload solubility and control spacing between payload and antibody or ligand, supporting efficient conjugation chemistry.
- Non-cleavable three-unit PEG linker suitable for ADC and PROTAC synthesis.
- Provides a short, hydrophilic spacer to improve solubility and reduce aggregation.
- High purity for consistent conjugation performance.
- Compatible with standard organic synthesis and conjugation workflows.
- Available in small research quantities for laboratory use.
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Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | MFCD29267156 | >98% | C38H77NO17 | 50 MG
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N-(Amino-PEG3)-N-bis(PEG4-Boc) is a building block and PEG linker used to synthesize various PEG-based linkers. It can easily react with activated NHS esters or carboxylic acid in the presence of EDC or HATU. The t-butyl group can be deprotected under acidic conditions, and it is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Easily reacts with activated NHS esters or carboxylic acid in the presence of EDC or HATU.
- t-butyl group can be deprotected under acidic conditions.
- Functions as a PEG-based PROTAC linker.
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Medchemexpress LLC m-PEG3-azide | 74654-06-1 | MFCD00020141 | >98% | C7H15N3O3 | 250 MG
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m-PEG3-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in various cycloaddition reactions.
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne groups.
- Can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
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Medchemexpress LLC Tert-butyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate | 252881-73-5 | 303.3547 g/mol | C13H25N3O5 | 50 MG
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N3-PEG3-CH2CH2-Boc is an azido-terminated PEG3 linker with a tert-butyl (Boc) protected carboxylic acid end, used as a cleavable PEG-based linker in antibody-drug conjugate and PROTAC synthesis, and as an azide reagent for click chemistry.
- Azide-terminated PEG3 linker suitable for click chemistry.
- tert-Butyl (Boc) protected carboxyl end for orthogonal deprotection.
- Used in ADC and PROTAC linker assembly.
- Available as a small pre-weighed laboratory pack for synthetic use.
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Medchemexpress LLC (S)-17-(4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzamido)-14-oxo-4,7,10-trioxa-13-azaoctadecane-1,18-dioic acid | 97.6% | C28H36N8O10 | 5 MG
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Folate-PEG3-C2-acid is an acid fragment and PEG-type PROTAC linker used in the synthesis of Proteolysis-targeting Chimeras. It has a molecular weight of 644.63 and a purity of 97.56%.
- Stable under recommended storage conditions
- Consistent with structure based on 1H NMR Spectrum and LCMS
- Solid appearance
- For research use only
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